CDK7 Assay Kit

• Description:

  Cyclin-dependent kinase 7 (CDK7) assembled with Cyclin H and MAT1 comprises an important sub-component of the transcription factor TFIIH. It is known to have dual roles, which include transcription regulation via phosphorylating the C-terminal domain (CTD) of RNA polymerase II as well as controlling cell cycle progression as a CDK activating kinase (CAK) . The CDK7 Assay Kit is designed to measure CDK7/Cyclin H/MAT1 activity for screening and profiling applications, using ADP-Glo® as a detection reagent.Need us to run inhibitor screens or profile your compounds against CDK7? Check out ourKinase Screening ServicesorDNA Replication and Repair Screening Services.This product has beencited 4 times.

• UniProt:

  Q24216

• Format:

  Catalog NumberComponentAmountStorage40098CDK7/Cyclin H/MAT110 µg-80°CAvoidfreeze/thawcycles!793345x Kinase assy buffer 11.5 ml-20°C79686ATP (500 µM) 100 µl-20°C79604CDK substrate peptide 2 (1 mg/ml) 125 µl-20°C7969696-well plate, white1Room Temp.

• Shipping Conditions:

  -80°C

• Storage Conditions:

  Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.