CDK1 Assay Kit

• Description:

  Cyclin-dependent kinases (CDKs) are key regulators of the cell cycle. CDKs are active only when bound to their regulator proteins, cyclins. CDK activity is tightly controlled for successful cell division. Since abnormal cell division represents cancer pathology, controlling CDK activity has been shown as a promising therapeutic strategy. In particular, CDK1 plays an important role in mitotic progression. The CDK1 Assay Kit is designed to measure CDK1/CyclinB1 activity for screening and profiling applications, using Kinase-Glo® MAX as a detection reagent.Need us to run inhibitor screens or profile your compounds against CDK1? Check out ourKinase Screening ServicesorDNA Replication and Repair Screening Services.This product has beencited 7 times.

• UniProt:

  CDK1: P06493; CyclinB1: P14635

• Format:

  CatalogNumberReagentAmountStorage40454CDK1/CyclinB12 µg-80°CAvoidmultiplefreeze/thawcycles!793345x Kinase assay buffer 11.5 ml-20°C79686ATP (500 µM) 100 µl-20°C7959810x CDK substrate peptide 1500 µl-20°C7969696-well plate, white1Room Temp.

• Shipping Conditions:

  -80°C

• Storage Conditions:

  Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.