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CDK4 Assay Kit

CAT: 0421-79674Size: 96 ReactionsDry Ice: YesHazardous: No
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CAT#:0421-79674Size:96 Reactions
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cyclin-dependent kinase 4 (CDK4) assembles with the ‘D’ type of Cyclins, e.g. cyclins D1, D2, and D3, and play a pivotal role in the cell cycle entering the S phase. Dysregulation of the activity of CDK4 is related to many different cancers, indicating CDK4 inhibitors as promising anticancer treatments. In fact, multiple CDK4 inhibitors, including Palbociclib, were approved by the FDA recently. The CDK4 Assay Kit is designed to measure CDK4/CyclinD3 activity for screening and profiling applications, using Kinase-Glo® Max as a detection reagent.This product has beencited 7 times.
UniProt
CDK4: P11802; CyclinD3: P30281
Format
Catalog NumberComponentAmountStorage40104CDK4/CyclinD320 µg-80°CAvoidfreeze/thawcycles!793345x Kinase assay buffer 11.5 ml-20°C79686ATP (500 µM) 100 µl-20°C7967510x CDK4 substrate peptide500 µl-20°C7969696-well plate, white1Room Temp.
Shipping Conditions
-80°C
Storage Conditions
Up to 6 months when stored as recommended.

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