DDX41 Antibody

CAT: 0800-V9206SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
CAT#:0800-V9206SAF-100UGSize:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DDX41 (Probable ATP-dependent RNA helicase DDX41, DEAD box protein abstrakt homolog) is a 622 amino acid protein encoded by the human gene DDX41. DDX41 belongs to the DEAD box helicase family (DDX41 subfamily) and contains one CCHC-type zinc finger, one helicase ATP-binding domain and one helicase C-terminal domain. DDX41 is required during post-transcriptional gene expression and is thought to be involved in pre-mRNA splicing. DDX41 is believed to be a probable ATP-dependent RNA helicase. RNA helicases are highly conserved enzymes that utilize the energy derived from NTP hydrolysis to modulate the structure of RNA. RNA helicases participate in all biological processes that involve RNA, including transcription, splicing and translation.
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells, Western blot: 1-2 µg/mL, Immunofluorescence: 1-2 µg/mL
UniProt
Q9UJV9
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human DDX41 protein was used as the immunogen for the DDX41 antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
PCRP-DDX41-1B4
Applications
FACS, WB, IF
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the DDX41 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This DDX41 antibody is available for research use only.
Storage Conditions
Aliquot the DDX41 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the DDX41 antibody should be determined by the researcher.
Location
Nucleus
Image Legend
Analysis of HuProt (TM) microarray containing more than 19,000 full-length human proteins using DDX41 antibody (clone PCRP-DDX41-1B4) . These results demonstrate the foremost specificity of the PCRP-DDX41-1B4 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt (TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt (TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Product Datasheet
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