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CD11b Antibody / MAC-1

CAT: 0800-V8135SAF-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V8135SAF-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Integrin ITGAM/ITGB2/CD11b/MAC-1 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P11215
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 941-1074 were used as the immunogen for this CD11b antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
CDLA11b-1
Applications
WB, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the CD11b antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD11b antibody is available for research use only.
Storage Conditions
Store the CD11b antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
The stated application concentrations are suggested starting points. Titration of the CD11b antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cell membrane, cytoplasm
Image Legend
IHC staining of FFPE human spleen with CD11b antibody (clone CDLA11b-1) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

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