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Bcl-X Antibody

CAT: 0800-V8062-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V8062-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recognizes a protein of 27kDa, identified as the Bcl-X protein. This MAb shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241-amino acid protein which suppresses cell death. And Bcl-XS (short), a 178-amino acid protein lacking a 63-amino acid domain which functions as a dominant inhibitor of Bcl-2.
CAS Number
9007-83-4
Specifications
Immunohistochemistry: 1-2 µg/mL
UniProt
Q07817
Host
Mouse
Reactivity
Human
Immunogen
A recombinant human partial protein (amino acids 1-135) was used as the immunogen for this Bcl-X antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
BCL2L1/2406
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the Bcl-X antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Bcl-X antibody is available for research use only.
Storage Conditions
Store the Bcl-X antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Bcl-X antibody should be determined by the researcher.
Location
Cytoplasmic and cell/nuclear membrane
Image Legend
IHC staining of FFPE human Hodgkin's lymphoma with Bcl-X antibody (clone BCL2L1/2406) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

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