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HNF1A Antibody

CAT: 0800-V7409IHC-7MLSize: 7 mLDry Ice: NoHazardous: No
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CAT#:0800-V7409IHC-7MLSize:7 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HNF1A is a transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. [UniProt]
CAS Number
9007-83-4
Specifications
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
UniProt
P20823
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 214-339 from the human protein was used as the immunogen for the HNF1A antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
HPTF1A-1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the HNF1A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This HNF1A antibody is available for research use only.
Storage Conditions
Store the HNF1A antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Nuclear
Image Legend
IHC staining of FFPE human small intestine with HNF1A antibody (clone HPTF1A-1) . HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.

UniProtKB · P20823

Hepatocyte nuclear factor 1-alpha

HNF1A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P20823
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HNF1A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
HNF-1-alpha, HNF-1A
EC number
—
Processing
—
Secondary accessions
A0A0A0MQU7, A5Z2R8, E0YMJ5, E0YMK0, E0YMK1, E2I9R4, E2I9R5, F5H5U3, Q2M3H2, Q99861
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Disease

Diabetes mellitusDisease variant

Domain

Homeobox

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Cellular component

Nucleus

Biological process

TranscriptionTranscription regulation

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