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HNF1A Antibody

CAT: 0800-V7409-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V7409-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HNF1A is a transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. [UniProt]
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
UniProt
P20823
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 214-339 from the human protein was used as the immunogen for the HNF1A antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
HPTF1A-1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the HNF1A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This HNF1A antibody is available for research use only.
Storage Conditions
Store the HNF1A antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Nuclear
Image Legend
IHC staining of FFPE human small intestine with HNF1A antibody (clone HPTF1A-1) . HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.

UniProtKB · P20823

Hepatocyte nuclear factor 1-alpha

HNF1A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P20823
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HNF1A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
HNF-1-alpha, HNF-1A
EC number
—
Processing
—
Secondary accessions
A0A0A0MQU7, A5Z2R8, E0YMJ5, E0YMK0, E0YMK1, E2I9R4, E2I9R5, F5H5U3, Q2M3H2, Q99861
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Disease

Diabetes mellitusDisease variant

Domain

Homeobox

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Cellular component

Nucleus

Biological process

TranscriptionTranscription regulation

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