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HNF1A Antibody

CAT: 0800-V7353-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-V7353-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicated HNF1A as a susceptibility gene for pancreatic cancer.
CAS Number
9007-83-4
Specifications
ELISA: order BSA/sodium azide-free format for coating, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P20823
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 214-339 from the human protein was used as the immunogen for the HNF1A antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
HNF1A/2087
Applications
ELISA, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the HNF1A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This HNF1A antibody is available for research use only.
Storage Conditions
Store the HNF1A antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Nuclear
Image Legend
IHC staining of FFPE human pancreas with HNF1A antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
Product Datasheet
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