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CCNA2 Antibody / Cyclin A2

CAT: 0800-V3783-20UGSize: 20 µgDry Ice: NoHazardous: No
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CAT#:0800-V3783-20UGSize:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CCNA2 is a Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine protein kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 or CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle. [Uniprot]
CAS Number
9007-83-4
Specifications
IHC (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P20248
Host
Mouse
Reactivity
Human
Immunogen
Full length protein was used as the immunogen for this CCNA2 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
CNA2-1
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the CCNA2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CCNA2 antibody is available for research use only.
Storage Conditions
Store the CCNA2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant CCNA2 antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic
Image Legend
IHC testing of FFPE human endometrial carcinoma with CCNA2 antibody (clone CNA2-1) . Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

UniProtKB · P20248

Cyclin-A2

CCNA2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P20248
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CCNA2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Cyclin-A
EC number
—
Processing
—
Secondary accessions
A8K7B6, Q2M3U6, Q4W5P4, Q6LER8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Biological process

Cell cycleCell divisionHost-virus interactionMitosis

Molecular function

Cyclin

Cellular component

CytoplasmNucleus

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