Products for Research Use Only
RegisterLogin

Cyclin A2 Antibody

CAT: 0800-R31999Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R31999Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cyclin A2, known as CCNA2, is mapped to 4q27. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. And Cyclin A2 is synthesized at the onset of S phase and localizes to the nucleus, where the cyclin A2-CDK2 complex is implicated in the initiation and progression of DNA synthesis. Phosphorylation of CDC6 and MCM4 by the cyclin A2-CDK2 complex prevents re-replication of DNA during the cell cycle.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence (FFPE) : 5 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
P20248
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids 10-168 of human Cyclin A2 were used as the immunogen for the Cyclin A2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF/ICC, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Cyclin A2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Cyclin A2 antibody is available for research use only.
Storage Conditions
After reconstitution, the Cyclin A2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Cyclin A2 antibody should be determined by the researcher.
Location
Cytoplasmic, nuclear
Image Legend
Immunofluorescent staining of FFPE human U-2 OS cells with Cyclin A2 antibody at 2ug/ml. HIER: steam section in pH6 citrate buffer for 20 min.

Related Products

CatalogName
V3783-20UGCCNA2 Antibody / Cyclin A2
V3783-100UGCCNA2 Antibody / Cyclin A2
V3783SAF-100UGCCNA2 Antibody / Cyclin A2
R30028Cyclin A Antibody
V7337-100UGCyclin D1 Antibody
V2946-100UGCyclin B1 Antibody
V2006IHC-7MLCyclin D1 Antibody
V3685SAF-100UGCyclin E1 Antibody
V7161IHC-7MLCyclin B1 Antibody
R32475Cyclin T1 Antibody

Alternative Products

CatalogName
MBS9435956-01Cyclin A1+ Cyclin A2 Antibody
abx134059-01Cyclin A1 (Cyclin A1) Antibody
abx133138-01Cyclin H (Cyclin H) Antibody
abx225081-01Cyclin D2 (Cyclin D2) Antibody
abx009484-01Cyclin E1 (Cyclin E1) Antibody
abx225079-01Cyclin A2 (Cyclin A2) Antibody
10R-7848Cyclin A antibody

Popular Products