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Cyclin A2 Antibody (CCNA2)

CAT: 0800-F50282-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F50282-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50
UniProt
P20248
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 358-389 from the human protein was used as the immunogen for this Cyclin A2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Cyclin A2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Cyclin A2 antibody is available for research use only.
Storage Conditions
Aliquot the Cyclin A2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Cyclin A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of Cyclin A2 antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the human gene (2) . Predicted molecular weight ~50 kDa

UniProtKB · P20248

Cyclin-A2

CCNA2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P20248
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CCNA2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Cyclin-A
EC number
—
Processing
—
Secondary accessions
A8K7B6, Q2M3U6, Q4W5P4, Q6LER8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Biological process

Cell cycleCell divisionHost-virus interactionMitosis

Molecular function

Cyclin

Cellular component

CytoplasmNucleus
Product Datasheet
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