Cyclin A2 Antibody / CCNA2

Cyclin A2 Antibody / CCNA2

• Description: This antibody recognizes a protein of 50-55 kDa, which is identified as Cyclin A. Cyclins are regulatory subunits of the cyclin-dependent kinases (cdk's) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdk's. These cyclin/cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, Cyclin A is required for S-phase and passage through G2-phase. The D and E type cyclins regulate the passage of G1, while Cyclin B is a critical regulator of mitosis. Mutation or disruption of normal Cyclin A expression causes cells to arrest in G2-phase.
• CAS Number: 9007-83-4
• UniProt: P20248
• Host: Mouse
• Immunogen: Full length protein was used as the immunogen for this CCNA2 antibody.
• Clonality: Monoclonal
• Isotype: IgG2a κ
• Applications: IHC-P
• Format: Purified
• Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Reconstitution: Store the Cyclin A2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This Cyclin A2 antibody is available for research use only.