Products for Research Use Only
RegisterLogin

CD8a Antibody Cocktail

CAT: 0800-V3134-20UGSize: 20 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-V3134-20UGSize:20 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8a/b) or as a homodimer (CD8a/a) . A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P01732
Host
Mouse
Reactivity
Human
Immunogen
Human recombinant protein (C8/468) and 13 amino acid peptide from the C-terminal cytoplasmic domain of the alpha chain of human CD8 (C8/144B) were used as the immunogens for this CD8a antibody cocktail.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
C8/468 + C8/144B
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the CD8a antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD8a antibody cocktail is available for research use only.
Storage Conditions
Store the CD8a antibody cocktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cell surface
Image Legend
IHC: Formalin-fixed, paraffin-embedded human tonsil stained with CD8a antibody (C8/468 + C8/144B) .

Related Products

CatalogName
V8824-100UGCD8A Antibody / CD8 alpha
V8824SAF-100UGCD8A Antibody / CD8 alpha
V8824-20UGCD8A Antibody / CD8 alpha
RQ5874Cd8a Antibody / CD8 alpha
V3139-20UGMyogenin Antibody Cocktail
V2027IHC-7MLCD1a Antibody Cocktail
V3156SAF-100UGMelan-A Antibody Cocktail
V2694SAF-100UGEpCAM Antibody Cocktail
V2455IHC-7MLChromogranin A Antibody Cocktail
V2937-20UGZAP70 Antibody Cocktail

Alternative Products

CatalogName
GTR18573088CD8a Antibody Cocktail
RD30551F-01Anti-Human CD3-APC/CD4-FITC/CD8a-PE Cocktail
E-AB-FC0002-01Anti-Human CD3-APC/CD4-FITC/CD8a-PerCP-Cyanine5.5 Cocktail
GTR18573512MITF Antibody Cocktail
GTR18573282PAX8 Antibody Cocktail
GTR18573097Myogenin Antibody Cocktail
GTR18572605SMMHC Antibody Cocktail
GTR18572397CD57 Antibody Cocktail
GTR18572387GFAP Antibody Cocktail
GTR18572177Chromogranin A Antibody Cocktail

Popular Products