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NK-252

CAT: 0804-HY-19734-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-19734-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NK-252 is a potential Nrf2 activator, which exhibits a great Nrf2-activating potential.
CAS Number
[1414963-82-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Keap1-Nrf2; Quinone Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/NK-252.html
Purity
99.60
Solubility
DMSO : ≥ 29 mg/mL
Smiles
O=C(NCC1=NC=CC=C1)NC2=NN=C(C3=CC=CO3)O2
Molecular Formula
C13H11N5O3
Molecular Weight
285.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Shimozono R et al. Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. Mol Pharmacol. 2013 Jul, 84 (1) :62-70.|[2]Kiue A, et al. Enhancement of antitumour activity of etoposide by dihydropyridines on drug-sensitive and drug-resistant leukaemia in mice. Br J Cancer. 1991 Aug;64 (2) :221-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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