NK-252

• UNSPSC Description:

  NK-252 is a potential Nrf2 activator, which exhibits a great Nrf2-activating potential.

• Target Antigen:

  Keap1-Nrf2

• Type:

  Reference compound

• Related Pathways:

  NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/NK-252.html

• Purity:

  99.48

• Solubility:

  DMSO : ≥ 29 mg/mL

• Smiles:

  O=C(NCC1=NC=CC=C1)NC2=NN=C(C3=CC=CO3)O2

• Molecular Weight:

  285.26

• References & Citations:

  [1]Shimozono R et al. Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. Mol Pharmacol. 2013 Jul, 84(1):62-70.|[2]Kiue A, et al. Enhancement of antitumour activity of etoposide by dihydropyridines on drug-sensitive and drug-resistant leukaemia in mice. Br J Cancer. 1991 Aug;64(2):221-6.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1414963-82-8