Anticancer agent 252

• Description :

  Anticancer agent 252 (compound 1) is a benzamide compound with selective anti-cancer activity against small cell lung cancer (SCLC) cells. Anticancer agent 252 inhibits murine SCLC (mSCLC) cell lines with an average EC50 of 3.21 μM. Anticancer agent 252 also inhibits human SCLC cell lines, H889, H2107, and H128[1].

• UNSPSC :

  12352005

• Target :

  Others

• Related Pathways :

  Others

• Field of Research :

  Cancer

• Smiles :

  O=C(C1=CC=C(Cl)C([N+]([O-])=O)=C1)N2CCN(C3=CC=CC=C3)CC2

• Molecular Formula :

  C17H16ClN3O3

• Molecular Weight :

  345.78

• References & Citations :

  [1]Povedano JM, et al. A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins. J Med Chem. 2020 Nov 25;63 (22) :14054-14066.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [314284-36-1]