BRAF Recombinant Antibody

BRAF Recombinant Antibody

• Description: The BRAF gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. [RefSeq]
• CAS Number: 9000-83-3
• UniProt: P15056
• Host: Rabbit
• Immunogen: A synthetic peptide specific to human B Raf was used as the immunogen for the BRAF antibody.
• Clonality: Monoclonal
• Isotype: IgG
• Type: Recombinant
• Applications: IHC-P, WB
• Format: Purified
• Buffer: Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
• Reconstitution: Store the BRAF antibody at -20oC.
• Limitations: This BRAF antibody is available for research use only.