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TLR5 Antibody

CAT: 0800-R31826Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31826Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TLR5 encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL, FACS: 1-3ug/10^6 cells
UniProt
O60602
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids MKHQSIRGFVQKQQYLRWPEDFQDVGWF of human TLR5 were used as the immunogen for the TLR5 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the TLR5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TLR5 antibody is available for research use only.
Storage Conditions
After reconstitution, the TLR5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TLR5 antibody should be determined by the researcher.
Location
Cytoplasmic, membrane
Image Legend
Western blot testing of Jurkat cell lysate with TLR5 antibody. Expected/observed molecular weight ~98 kDa.

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