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TLR2 Antibody

CAT: 0800-RQ4761Size: 100 µLDry Ice: NoHazardous: No
CAT#:0800-RQ4761Size:100 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Toll-like Receptor 2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs) . Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. [RefSeq]
CAS Number
9000-83-3
Specifications
Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:100-1:500
UniProt
O60603
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic peptide specific to human TLR2 was used as the immunogen for the TLR2 antibody.
Clonality
Monoclonal
Isotype
IgG
Clone
ADH-20
Type
Recombinant
Applications
IHC-P, WB
Purity
Affinity purified
Format
Purified
Buffer
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
Reconstitution
Store the TLR2 antibody at -20oC.
Limitations
This TLR2 antibody is available for research use only.
Storage Conditions
Store the TLR2 antibody at -20°C.
Formulation
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA
Applications Notes
Optimal dilution of the TLR2 antibody should be determined by the researcher.
Image Legend
IHC staining of FFPE human kidney tissue with TLR2 antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.

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