TLR2 Antibody
CAT:
800-F44370-0.08ML
Size:
0.08 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
TLR2 Antibody
- Description: TLR2 cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6. [UniProt]
- CAS Number: 9007-83-4
- UniProt: O60603
- Host: Rabbit
- Immunogen: A portion of amino acids 212-242 from the human protein was used as the immunogen for this TLR2 antibody.
- Clonality: Polyclonal
- Isotype: Ig
- Applications: WB, IHC, FACS, ELISA
- Format: Purified
- Buffer: In 1X PBS pH 7.4 with 0.09% sodium azide
- Reconstitution: Aliquot the TLR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This TLR2 antibody is available for research use only.