Cdk7 Antibody

CAT: 0800-R31240Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R31240Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cyclin-dependent kinase 7, also known as Cell division protein kinase 7, is an enzyme that in humans is encoded by the CDK7 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. The gene was assigned to human chromosome 5q13.2. Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex. It is required for DNA-bound peptides-mediated transcription and cellular growth inhibition.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P50613
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
An amino acid sequence from the C-terminus of human Cyclin-dependent kinase 7 (RKRTEALEQGGLPKKLIF) was used as the immunogen for this Cdk7 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the Cdk7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Cdk7 antibody is available for research use only.
Storage Conditions
After reconstitution, the Cdk7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the Cdk7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of Cdk7 antibody and Lane 1: HeLa; 2: MCF-7; 3: A549; 4: COLO320; 5: Jurkat cell lysate. Expected/observed molecular weight ~37 kDa.

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