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ABCG2 Antibody (BCRP)

CAT: 0800-R30969Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30969Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABCG2 (ATP-binding cassette, subfamily G, member 2) also known as ABCP, BCRP (Breast cancer resistance protein) or MRX (Mitoxantrone resistance-associated protein), is a protein that in humans is encoded by the ABCG2 gene. The gene encodes a membrane transporter belonging to the ATP-binding cassette (ABC) superfamily of membrane transporters, which are involved in the trafficking of biologic molecules across cell membranes.The protein is also a high capacity transporter for uric acid excretion in the kidney, liver, and gut. In vitro assays of isolated membrane preparations revealed a high-capacity, vanadate-sensitive ATPase activity associated with ABCG2 expression that was stimulated by compounds known to be transported by this protein.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q7TMS5
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Amino acids 152-167 (KNHEKNERINTIIKEL-mouse) were used as the immunogen for this BCRP / ABCG2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
The lyophilized ABCG2 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ABCG2 antibody is available for research use only.
Storage Conditions
The lyophilized ABCG2 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Titration of the ABCG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of ABCG2 antibody and Lane 1: rat liver; 2: rat spleen; 3: rat kidney; 4: mouse spleen tissue lysate. Predicted molecular weight ~72kDa.
Product Datasheet
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