ABCG2 Antibody

CAT: 0800-F44284-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
CAT#:0800-F44284-0.4MLSize:0.4 mL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ABCG2 is a membrane-associated protein included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.
CAS Number
9007-83-4
UniProt
Q9UNQ0
Host
Rabbit
Immunogen
A portion of amino acids 305-335 from the human protein was used as the immunogen for this ABCG2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IF, FACS, IHC, ELISA
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ABCG2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ABCG2 antibody is available for research use only.

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