Cdk5 Antibody
CAT:
800-R30624
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Cdk5 Antibody
- Description: Cyclin-Dependent Kinase 5, is also know as PSSALRE. The p34(CDC2) protein kinase regulates important transitions in the eukaryotic cell cycle. Cdk5 expression is in all human tissues and cell lines tested. The the gene is mapped to chromosome 7q36. Cyclin-dependent kinase 5 is predominantly expressed in neurons where it phosphorylates both high molecular weight neurofilaments and microtubule-associated protein tau. It is required for proper development of the mammalian central nervous system. To be activated, Cdk5 must associate with its regulatory subunit, p35(CDK5R1). It can phosphorylate DARPP32 at threonine-75, converting it into an inhibitor of PKA.
- CAS Number: 9007-83-4
- UniProt: Q00535
- Host: Rabbit
- Immunogen: An amino acid sequence from the C-terminus of human Cdk5 (QRISAEEALQHPYFSDFCPP) was used as the immunogen for this Cdk5 antibody (100% homologous in human, mouse and rat).
- Clonality: Polyclonal
- Isotype: IgG
- Applications: WB
- Format: Antigen affinity purified
- Buffer: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
- Reconstitution: After reconstitution, the Cdk5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
- Limitations: This Cdk5 antibody is available for research use only.