Products for Research Use Only
RegisterLogin

Caspase-6 Antibody

CAT: 0800-R30512Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R30512Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Caspase-6 is an enzyme that in humans is encoded by the CASP6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease family. Using radiation hybrid mapping, the CASP6 gene was localized to human chromosome 4q25-q26. It functions as a downstream enzyme in the caspase activation cascade, and can cleave Lamin A to its signature apoptotic fragment.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells
UniProt
P55212
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids 24-44 (AFYKREMFDPAEKYKMDHRRR-human) were used as the immunogen for this Caspase-6 antibody. This sequence is from the large subunit.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
After reconstitution, the Caspase-6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Caspase-6 antibody is available for research use only.
Storage Conditions
After reconstitution, the Caspase-6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting points. Titration of the Caspase-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
IHC staining of FFPE human colorectal adenocarcinoma tissue with Caspase-6 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.

UniProtKB · P55212

Caspase-6

CASP6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P55212
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CASP6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CASP-6, CSP-6
EC number
3.4.22.59
Processing
Precursor
Secondary accessions
Q9BQE7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Apoptosis

PTM

Autocatalytic cleavageLipoproteinPalmitatePhosphoproteinZymogen

Cellular component

CytoplasmNucleus

Molecular function

HydrolaseProteaseThiol protease

Related Products

CatalogName
FY12753CASP6 Antibody / Caspase 6
F48960-0.4MLCaspase-3 Antibody
R36146-100UGCaspase 12 Antibody
F42862-0.4MLCaspase-2 Antibody
F52416-0.4MLCaspase-3 Antibody
F50514-0.4MLCaspase-3 Antibody
R32146Caspase-7 Antibody
F41865-0.4MLCaspase-12 Antibody
RQ4905Caspase 3 Antibody
F52416-0.08MLCaspase-3 Antibody

Alternative Products

CatalogName
GTR18075210-01Caspase-6 Antibody
GTR18125516Caspase 6 Antibody

Popular Products