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Caspase-7 Antibody

CAT: 0800-R32146Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32146Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Caspase-7, Apoptosis-related cysteine peptidase, is a human protein encoded by the CASP7 gene. CASP7 orthologs have been identified in nearly all mammals for which complete genome data are available. It is a member of the caspase (cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of CASP7 regulates microglia activation through a protein kinase C-delta (PRKCD) -dependent pathway.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
P55210
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids 117-198 of human Caspase-7 were used as the immunogen for the Caspase-7 antibody. This sequence is from the large subunit.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trelahose
Reconstitution
After reconstitution, the Caspase-7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Caspase-7 antibody is available for research use only.
Storage Conditions
After reconstitution, the Caspase-7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Caspase-7 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Western blot testing of 1) human A549, 2) rat spleen and 3) rat lung lysate using Caspase-7 antibody. Expected/observed molecular weight ~34 kDa (full length) .

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