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Bcl-XS Antibody

CAT: 0800-R30334Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30334Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bcl-XS is the second mRNA species of Bcl-X protein, which encodes a protein that inhibits the ability of Bcl-2 to enhance the survival of growth factor-deprived cells. In vivo, Bcl-XS mRNA is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. Apoptosis was associated with increased protein expression of Bcl-XS, an early marker of apoptosis, and release of Cytochrome C into the cytosol of infected HB cells.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
Q07817
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids 120-130 (YQSFEQDTFVE-human) were used as the immunogen for this Bcl-XS antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the Bcl-XS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Bcl-XS antibody is available for research use only.
Storage Conditions
After reconstitution, the Bcl-XS antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting points. Titration of the Bcl-XS antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of 1) human HeLa and 2) rat PC-12 cell lysate with Bcl-XS antibody. Predicted/observed molecular weight: ~19 kDa.

UniProtKB · Q07817

Bcl-2-like protein 1

B2CL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q07817
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BCL2L1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Bcl2-L-1
EC number
—
Processing
—
Secondary accessions
E1P5L6, Q5CZ89, Q5TE65, Q92976
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisEndocytosis

Cellular component

CytoplasmCytoplasmic vesicleCytoskeletonMembraneMitochondrionMitochondrion inner membraneMitochondrion outer membraneNucleusSynapse

PTM

PhosphoproteinUbl conjugation

Domain

TransmembraneTransmembrane helix

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ASA-B0204Bcl-XS Antibody
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GTR18530464Bcl-XS/BCL2L1/XS Rabbit Polyclonal Antibody (HRP)
GTR18530466Bcl-XS/BCL2L1/XS Rabbit Polyclonal Antibody (Cy3)
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