Beta-Actin Antibody

• Description:

  The primary site of action of cytochalasin B on cell motility processes is beta-actin. Habets et al.(1992) generated hybrids that harbor only specific regions of human chromosome 7 and assigned the ACTB locus to 7p15-p12. ACTB and the other assigned beta-actin-related sequences are dispersed over at least four different chromosomes including one locus assigned to the X chromosome. A mutation of the protein that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.

• Host:

  Mouse

• Immunogen:

  Amino acids DDDIAALVIDNGSGK were used as the immunogen for this beta-Actin antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Applications:

  WB, IHC-P

• Format:

  Ascites

• Buffer:

  0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS

• Reconstitution:

  After reconstitution, the beta-Actin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This beta-Actin antibody is available for research use only.

• CAS Number:

  9007-83-4