TLR3 Antibody

• Description :

  Toll like Receptor 3 is a key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. [UniProt]

• Specifications :

  Western blot: 1:1000

• UniProt :

  O15455

• Host :

  Mouse

• Reactivity :

  Human

• Immunogen :

  A human recombinant partial protein was used as the immunogen for this TLR3 antibody.

• Clonality :

  Monoclonal

• Isotype :

  IgG2b

• Clone :

  2F10-B8-G9

• Applications :

  WB

• Purity :

  Protein G affinity

• Format :

  Purified

• Buffer :

  Antibody in PBS with 50% Glycerol and 0.03% ProClin 300

• Reconstitution :

  Store the TLR3 antibody at -20oC.

• Limitations :

  This TLR3 antibody is available for research use only.

• Storage Conditions :

  Store the TLR3 antibody at -20°C.

• Formulation :

  In PBS with 50% glycerol and 0.03% ProClin 300

• Applications Notes :

  The stated application concentrations are suggested starting points. Titration of the TLR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number :

  9007-83-4

• Image Legend :

  Western blot testing of TLR3 A) transfected and (B) untransfected CHO-K1 cell lysate with TLR3 antibody at 1:1000. Expected molecular weight of the partial protein: ~50 kDa.