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TLR3 Antibody

CAT: 0800-F54042-0.1MLSize: 0.1 mLDry Ice: NoHazardous: No
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CAT#:0800-F54042-0.1MLSize:0.1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Toll like Receptor 3 is a key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. [UniProt]
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
O15455
Host
Mouse
Reactivity
Human
Immunogen
A human recombinant partial protein was used as the immunogen for this TLR3 antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
2F10-B8-G9
Applications
WB
Purity
Protein G affinity
Format
Purified
Buffer
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Reconstitution
Store the TLR3 antibody at -20oC.
Limitations
This TLR3 antibody is available for research use only.
Storage Conditions
Store the TLR3 antibody at -20°C.
Formulation
In PBS with 50% glycerol and 0.03% ProClin 300
Applications Notes
The stated application concentrations are suggested starting points. Titration of the TLR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of TLR3 A) transfected and (B) untransfected CHO-K1 cell lysate with TLR3 antibody at 1:1000. Expected molecular weight of the partial protein: ~50 kDa.

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