Aβ/tau aggregation-IN-3

• CAS Number:

  1210750-32-5

• UNSPSC Description:

  Aβ/tau aggregation-IN-3 is a potent amyloid protein aggregation inhibitor with an IC50 of 0.85 μM by Aβ-Thioflavin T (Aβ-ThT) functional aggregation assay. Aβ/tau aggregation-IN-3 has anti-amyloid activity[1].

• Target Antigen:

  Amyloid-β

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/aβ-tau-aggregation-in-3.html

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(N1CCN(CC1)C2=CC=C([N+]([O-])=O)C(NC3=CC=CC=C3)=C2)C4=CC=CC=C4

• Molecular Weight:

  402.45

• References & Citations:

  [1]Christopher J. Barden, et al. Methods for identifying inhibitors of amyloid protein aggregation. US20160283652A1.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported