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DKK-1 Antibody

CAT: 0800-F51803-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F51803-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DKK-1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
O94907
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 58-84 from the human protein was used as the immunogen for this DKK-1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the DKK-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This DKK-1 antibody is available for research use only.
Storage Conditions
Aliquot the DKK-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the DKK-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of DKK-1 antibody and T47D lysate. Predicted molecular weight: 26-40 kDa depending on glycosylation level.

UniProtKB · O94907

Dickkopf-related protein 1

DKK1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O94907
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DKK1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Dickkopf-1, Dkk-1, hDkk-1
EC number
—
Processing
Precursor
Secondary accessions
B2RC19
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

Developmental protein

PTM

Disulfide bondGlycoprotein

Cellular component

Secreted

Domain

Signal

Biological process

Wnt signaling pathway

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