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Phenacetin

CAT: 0013-GTR19161203-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19161203-01Size:500 mg
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Description
Phenacetin is a non-opioid analgesic without anti-inflammatory properties. Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action on the heart, where it acts as a negative inotrope. Phenacetin is an antipyretic, acting on the brain to decrease the temperature set point. Phenacetin is also used to treat rheumatoid arthritis (subacute type) and intercostal neuralgia. (In Vitro) :Phenacetin shows inhibitory activity for COX-3 with an IC50 value of 102 μM in insect cells .Phenacetin is a substrate widely used as an in vitro and in vivo probe to measure the activity of CYP1A2, because the metabolism of phenacetin to acetaminophen is thought to be a selective CYP1A2-mediated reaction. (In Vivo) :Phenacetin exhibits elimination half-life (rat 2.06 h) and Cmax (6,728.3 μg/L) following oral administration (rat 20 mg/kg) .
CAS Number
62-44-2
Product Name Alternative
P-Acetophenetidide | 4′-Ethoxyacetanilide | NSC 7651
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 36 mg/mL (200.87 mM) ; DMSO: 36 mg/mL (200.87 mM)
Smiles
CC (NC1=CC=C (OCC) C=C1) =O
Molecular Formula
C10H13NO2
Molecular Weight
179.22
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (4-Ethoxyphenyl) acetamide

Alternative Products

CatalogName
B1453-1000Phenacetin

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