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HNF1A Antibody

CAT: 0800-F51309-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F51309-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HNF1A is a transcription factor required for the expression of several liver-specific genes. This protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Immunofluorescence: 1:10-1:50
UniProt
P20823
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 177-205 from the human protein was used as the immunogen for this HNF1A antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IF, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the HNF1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This HNF1A antibody is available for research use only.
Storage Conditions
Aliquot the HNF1A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the HNF1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Rat
Image Legend
Confocal immunofluorescent analysis of HNF1A antibody with HepG2 cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green) . DAPI was used as a nuclear counterstain (blue) .

UniProtKB · P20823

Hepatocyte nuclear factor 1-alpha

HNF1A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P20823
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HNF1A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
HNF-1-alpha, HNF-1A
EC number
—
Processing
—
Secondary accessions
A0A0A0MQU7, A5Z2R8, E0YMJ5, E0YMK0, E0YMK1, E2I9R4, E2I9R5, F5H5U3, Q2M3H2, Q99861
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Disease

Diabetes mellitusDisease variant

Domain

Homeobox

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Cellular component

Nucleus

Biological process

TranscriptionTranscription regulation

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