PAK4 Antibody
CAT:
800-F50893-0.4ML
Size:
0.4 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PAK4 Antibody
- Description: PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.
- CAS Number: 9007-83-4
- UniProt: O96013
- Host: Rabbit
- Immunogen: A portion of amino acids 156-187 from the human protein was used as the immunogen for this PAK4 antibody.
- Clonality: Polyclonal
- Isotype: Ig
- Applications: IHC, WB, ELISA
- Format: Purified
- Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
- Reconstitution: Aliquot the PAK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This PAK4 antibody is available for research use only.