PAK6 Antibody

CAT: 0800-F50895-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
CAT#:0800-F50895-0.4MLSize:0.4 mL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The PAK6 protein shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. PAK6 was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q9NQU5
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 116-146 from the human protein was used as the immunogen for this PAK6 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PAK6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PAK6 antibody is available for research use only.
Storage Conditions
Aliquot the PAK6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the PAK6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of PAK6 antibody in lysate from transiently transfected COS7 cells. Lane 1: negative control, 2: PAK1, 3: PAK2, 4: PAK4, 5: PAK5, and 6: PAK6-expressing cells.

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E45R17745G-1PAK6 Antibody

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