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CYP26A1 Antibody

CAT: 0800-F40123-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F40123-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CYP26A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
O43174
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 118-147 from the human protein was used as the immunogen for this CYP26A1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the CYP26A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CYP26A1 antibody is available for research use only.
Storage Conditions
Aliquot the CYP26A1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CYP26A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of CYP26A1 antibody and Jurkat lysate

UniProtKB · O43174

Cytochrome P450 26A1

CP26A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O43174
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CYP26A1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CYP26A1
EC number
1.14.13.-
Processing
—
Secondary accessions
B3KNI4, Q5VXH9, Q5VXI0
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Endoplasmic reticulumMembraneMicrosome

Ligand

HemeIronMetal-binding

Biological process

Lipid metabolism

Molecular function

MonooxygenaseOxidoreductase

Technical term

Proteomics identificationReference proteome

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