DHC-156

• Description:

  DHC-156 is a selective Brachyury small molecule downmodulator. DHC-156 can be used for chordoma research[1].

• UNSPSC:

  12352005

• Target:

  Wnt

• Type:

  Reference compound

• Related Pathways:

  Stem Cell/Wnt

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dhc-156.html

• Purity:

  99.54

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  COC1=C(C=C2C(C=CN=C2NC3=CC(OCC(F)(F)F)=C(C=C3)F)=C1)NC(/C=C/CN(C)C)=O

• Molecular Formula:

  C24H24F4N4O3

• Molecular Weight:

  492.47

• References & Citations:

  [1]Chase DH, et al. Development of a Small Molecule Downmodulator for the Transcription Factor Brachyury. Angew Chem Int Ed Engl. 2024 Feb 13:e202316496

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported