WB-156

• Target:

  MDM-2/p53

• Related Pathways:

  Apoptosis

• Bioactivity:

  WB-156 is an MDM2 PROTAC with an IC50 of 3.2 nM that facilitates the degradation of MDM2.

• Smiles:

  C (=O) (N1[C@@H] ([C@@H] (N=C1C2=C (OCC) C=C (C (C) (C) C) C=C2) C3=CC=C (Cl) C=C3) C4=CC=C (Cl) C=C4) N5CCN (CC#CC6=C7C (C (=O) N (C7) C8C (=O) NC (=O) CC8) =CC=C6) CC5

• Molecular Formula:

  C48H48Cl2N6O5

• Molecular Weight:

  859.84

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2368944-44-7