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TachypleginA

CAT: 0804-HY-114909Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-114909Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TachypleginA can inhibit the motility of T. gondii by binding directly and covalently to C58 of TgMLC1, thereby causing a decrease in the activity of the parasite's myosin motor[1].
CAS Number
331839-29-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tachyplegina.html
Smiles
FC1=CC=C(C=C1)/C=C2CN(C/C(C\2=O)=C\C3=CC=C(C=C3)F)CCC
Molecular Formula
C22H21F2NO
Molecular Weight
353.41
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Leung JM, et al. Identification of T. gondii myosin light chain-1 as a direct target of TachypleginA-2, a small-molecule inhibitor of parasite motility and invasion. PLoS One. 2014;9 (6) :e98056. Published 2014 Jun 3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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