Tachyplesin II

CAT: 0804-HY-P11398Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P11398Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Tachyplesin II is a broad-spectrum cationic antimicrobial peptide. Tachyplesin II has significant inhibitory effects on Gram-positive bacteria, Gram-negative bacteria, and some fungi. Tachyplesin II binds to bacterial membrane lipopolysaccharides through its positive charge, disrupting membrane integrity and causing leakage of cellular contents. Tachyplesin II can bind to DNA grooves, inhibiting microbial replication, and also suppressing HIV-1 replication and the proliferation of liver cancer cells[1].
UNSPSC
12352209
Target
Bacterial; DNA Alkylator/Crosslinker; Fungal; HIV
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Cancer; Infection
Smiles
O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)NC3=O)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCCNC(N)=N)C(N[C@H]3CCCCN)=O)=O)=O)NC6=O)C(N[C@@H](CC7=CC=C(C=C7)O)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@H]6[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N
Molecular Formula
C99H150N34O20S4
Molecular Weight
2264.73
References & Citations
[1]Xu F, et al. Eukaryotic expression and antimicrobial spectrum determination of the peptide tachyplesin II. Protein Expr Purif. 2008 Apr;58 (2) :175-83.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P1632-01Tachyplesin I
HY-P11399Tachyplesin-3
HY-P1632ATachyplesin I (TFA)
HY-E70038Endoglycoceramidase II (EGCase II)
HY-E70283Recombinant endoglycoceramidase II assisted by activator II
HY-N5174Azetomycin II
HY-N16848Foeniculoside II
HY-N15047Barminomycin II
HY-N14611Pyrazomycin II
HY-KE7034Sac II

Alternative Products

CatalogName
M40825-01Tachyplesin I
MBS407573-01Tachyplesin III
TP3137-01Tachyplesin I TFA
MBS1124130-01Recombinant Tachypleus tridentatus Tachyplesin-2
MBS1174034-01Recombinant Tachypleus gigas Tachyplesin-3
MBS1012305-01Recombinant Carcinoscorpius rotundicauda Tachyplesin-1
MBS1227561-01Recombinant Tachypleus tridentatus Tachyplesin-1
MBS1167157-01Recombinant Tachypleus gigas Tachyplesin-1

Popular Products