Anticancer agent 191

CAT: 0804-HY-157876Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-157876Size:1 Each
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Anticancer agent 191 (Compound 2) is a derivative of probenecid (HY-B0545) . As a cancer cell efflux inhibitor, Anticancer agent 191 is designed to inhibit P-glycoprotein (P-gp), breast cancer resistance protein (BCRP), and/or multiple multidrug resistance proteins (MRPs) . Anticancer agent 191 increases the accumulation of vinblastine in cancer cells, which is used for cancer research[1].
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
BCRP; P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-191.html
Solubility
10 mM in DMSO
Smiles
CCCN(S(=O)(C1=CC=C(C=C1)C(NCCCC[C@H](C(O)=O)N)=O)=O)CCC
Molecular Formula
C19H31N3O5S
Molecular Weight
413.53
References & Citations
[1]Huttunen J, et al. Amino acid derivative of probenecid potentiates apoptosis-inducing effects of vinblastine by increasing oxidative stress in a cancer cell-specific manner. Chem Biol Interact. 2024 Jan 25;388:110833.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Popular Products