HNS-32

• UNSPSC Description:

  HNS-32 is a compound with antiarrhythmic and vasodilatory effects in canine hearts, showing superior protective effects against ischemic and reperfusion arrhythmias compared to an equivalent dose of Mexiletine hydrochloride (HY-A0093). Furthermore, HNS-32 exhibits significant negative chronotropic effects on mammalian ventricular myocardium, indicating its potential application value in the study of acute coronary syndrome[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/hns-32.html

• Smiles:

  CC1=C2C(/C(N(C)C)=N\CC3=NC=CC=C3)=CC(C)=C2C=C(C(C)C)C=C1

• Molecular Weight:

  359.51

• References & Citations:

  [1]Saitoh, et al. "Effects of HNS-32, a novel antiarrhythmic drug, on ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats." Molecular and Cellular Biochemistry 205 (2000): 133-140.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  186086-10-2