2-Hydroxyacetophenone

• UNSPSC Description:

  2-Hydroxyacetophenone is a principal root volatile of the Carissa edulis[1]. 2-Hydroxyacetophenone shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 1.8 mM[2].

• Target Antigen:

  HIV; SARS-CoV

• Type:

  Natural Products

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/2-hydroxyacetophenone.html

• Purity:

  99.91

• Solubility:

  DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(C1=CC=CC=C1)CO

• Molecular Weight:

  136.15

• References & Citations:

  [1]M D Bentley, et al. 2-Hydroxyacetophenone: principal root volatile of the East African medicinal plant, Carissa edulis. J Nat Prod. Nov-Dec 1984;47(6):1056-7.|[2]Min Zhuang, et al. Procyanidins and butanol extract of Cinnamomi Cortex inhibit SARS-CoV infection. Antiviral Res. 2009 Apr;82(1):73-81.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  582-24-1