4-Hydroxyacetophenone

• Description:

  4-Hydroxyacetophenone (P-hydroxyacetophenone) is a major hepatoprotective and choleretic compound found in Artemisia and Illicium plants, exhibiting antiviral and anti-inflammatory effects against hepatitis B virus. Additionally, 4-Hydroxyacetophenone inhibits cancer cell adhesion, invasion, and migration by remodeling actin. 4-Hydroxyacetophenone holds promise for research in the fields of inflammatory diseases and cancer[1][2].

• Product Name Alternative:

  P-hydroxyacetophenone

• UNSPSC:

  12352005

• Hazard Statement:

  H319, H412

• Target:

  HBV; Myosin

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Cytoskeleton

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Cancer; Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/4-hydroxyacetophenone.html

• Concentration:

  10mM

• Purity:

  99.99

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC(C1=CC=C(O)C=C1)=O

• Molecular Formula:

  C8H8O2

• Molecular Weight:

  136.15

• Precautions:

  H319, H412

• References & Citations:

  [1]Ching-Wen C, et al. p-Hydroxyacetophenone suppresses nuclear factor-κB-related inflammation in nociceptive and inflammatory animal models. J Nat Med. 2017 Apr;71 (2) :422-432.|[2]Bryan DS, et al. 4-Hydroxyacetophenone modulates the actomyosin cytoskeleton to reduce metastasis. Proc Natl Acad Sci U S A. 2020 Sep 8;117 (36) :22423-22429.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [99-93-4]