4-Hydroxyacetophenone oxime

CAT: 0804-HY-135325-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-135325-01Size:5 mg
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Description
4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol) . Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic agent[1][2].
CAS Number
[34523-34-7]
UNSPSC
12352005
Hazard Statement
H228, H302, H317, H319, H341, H351
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/4-hydroxyacetophenone-oxime.html
Purity
99.96
Solubility
DMSO : ≥ 100 mg/mL
Smiles
C/C(C1=CC=C(O)C=C1)=N\O
Molecular Formula
C8H9NO2
Molecular Weight
151.16
Precautions
H228, H302, H317, H319, H341, H351
References & Citations
[1]Hinz, B, et al. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J, 2008. 22 (2) : p. 383-90.|[2]Rothen JP, et al. Acetaminophen is an inhibitor of hepatic N-acetyltransferase 2 in vitro and in vivo. Pharmacogenetics. 1998 Dec;8 (6) :553-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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