4-Hydroxyacetophenone oxime

• Description :

  4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol) . Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic agent[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H228, H302, H317, H319, H341, H351

• Target :

  Drug Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/4-hydroxyacetophenone-oxime.html

• Purity :

  99.96

• Solubility :

  DMSO : ≥ 100 mg/mL

• Smiles :

  C/C(C1=CC=C(O)C=C1)=N\O

• Molecular Formula :

  C8H9NO2

• Molecular Weight :

  151.16

• Precautions :

  H228, H302, H317, H319, H341, H351

• References & Citations :

  [1]Hinz, B, et al. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J, 2008. 22 (2) : p. 383-90.|[2]Rothen JP, et al. Acetaminophen is an inhibitor of hepatic N-acetyltransferase 2 in vitro and in vivo. Pharmacogenetics. 1998 Dec;8 (6) :553-9.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, stored under nitrogen)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [34523-34-7]