3-Hydroxyacetophenone

• Description:

  3-Hydroxyacetophenone (m-Hydroxyacetophenone) is a hydroxy-substituted alkyl phenyl ketone and also a plant defensin in carnations. 3-Hydroxyacetophenone has antifusarium activity. In addition, 3-Hydroxyacetophenone can be used to synthesize Rivastigmine (HY-17368) [1][2][3].

• Product Name Alternative:

  M-Hydroxyacetophenone

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319, H402

• Target:

  Drug Intermediate; Fungal

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/3-hydroxyacetophenone.html

• Concentration:

  10mM

• Purity:

  99.99

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC(C1=CC=CC(O)=C1)=O

• Molecular Formula:

  C8H8O2

• Molecular Weight:

  136.15

• Precautions:

  H315, H319, H402

• References & Citations:

  [1]Katharine Moore Tibbetts, et al. Controlling dissociation of alkyl phenyl ketone radical cations in the strong-field regime through hydroxyl substitution position. J Phys Chem A. 2014 Sep 18;118 (37) :8170-6.|[2]Kiwon Han, et al. Chemoenzymatic synthesis of rivastigmine via dynamic kinetic resolution as a key step. J Org Chem. 2010 May 7;75 (9) :3105-8.|[3]Curir P, et al. 3-Hydroxyacetophenone in carnations is a phytoanticipin active against Fusarium oxysporum f. sp. dianthi. Phytochemistry, 1996, 41 (2) : 447-450.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  121-71-1