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2-Bromo-4'-hydroxyacetophenone

CAT: 0804-HY-W002314-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W002314-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2-Bromo-4'-hydroxyacetophenone is a PTP1B inhibitor with a Ki value of 42 μM. 2-Bromo-4'-hydroxyacetophenone is also an intermediate. 2-Bromo-4'-hydroxyacetophenone can be used in the synthesis of LXRα/β antagonists. 2-Bromo-4'-hydroxyacetophenone can be used in research on hematological diseases[1][2].
CAS Number
2491-38-5
UNSPSC
12352005
Hazard Statement
H302, H319
Target
Drug Intermediate; Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/2-bromo-4-hydroxyacetophenone.html
Purity
98.59
Solubility
DMSO : 200 mg/mL (ultrasonic) |Methanol : 125 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C(CBr)=O)C=C1
Molecular Formula
C8H7BrO2
Molecular Weight
215.05
Precautions
H302, H319
References & Citations
[1]Sidhu, Alban, et al. Toward Inhibitors of Protein Tyrosine Phosphatases for Cancer Treatment. Home / Current Enzyme Inhibition, Volume 4, Number 1.|[2]Nian S, et al. Discovery and Synthesis of a Novel Series of Liver X Receptor Antagonists. Chem Pharm Bull (Tokyo) . 2015;63 (8) :628-35.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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