IN-RNA-IN-2

IN-RNA-IN-2

• UNSPSC Description: IN-RNA-IN-2 (compound 1a) is an inhibitor (IC50=70 nM) of the interaction between HIV-1 integrase and the viral RNA genome. IN-RNA-IN-2 exerts its anti-HIV activity by inhibiting the viral replication process[1].
• Target Antigen: HIV; HIV Integrase
• Type: Reference compound
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/in-rna-in-2.html
• Smiles: O=C(O)C(/C(O)=C/C(C1=CN(CC2=CC=C(F)C=C2)C3=C(C=C(C(/C=C(C(O)=O)\O)=O)C=C3)C1=O)=O)=O
• Molecular Weight: 509.39
• References & Citations: [1]Patacchini, et al. "Quinolinonyl Derivatives as Dual Inhibitors of the HIV-1 Integrase Catalytic Site and Integrase–RNA interactions." ACS Medicinal Chemistry Letters (2024).
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported