IN-RNA-IN-2

• UNSPSC Description:

  IN-RNA-IN-2 (compound 1a) is an inhibitor (IC50=70 nM) of the interaction between HIV-1 integrase and the viral RNA genome. IN-RNA-IN-2 exerts its anti-HIV activity by inhibiting the viral replication process[1].

• Target Antigen:

  HIV; HIV Integrase

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Metabolic Enzyme/Protease

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/in-rna-in-2.html

• Smiles:

  O=C(O)C(/C(O)=C/C(C1=CN(CC2=CC=C(F)C=C2)C3=C(C=C(C(/C=C(C(O)=O)\O)=O)C=C3)C1=O)=O)=O

• Molecular Weight:

  509.39

• References & Citations:

  [1]Patacchini, et al. "Quinolinonyl Derivatives as Dual Inhibitors of the HIV-1 Integrase Catalytic Site and Integrase–RNA interactions." ACS Medicinal Chemistry Letters (2024).

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported