RNA polymerase-IN-1

RNA polymerase-IN-1

• CAS Number: 2447106-74-1
• UNSPSC Description: RNA polymerase-IN-1 (compound 4) is s DNA-dependent RNA polymerase inhibitor. RNA polymerase-IN-1 inhibits CYP isozymes[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/rna-polymerase-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]([C@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H](OC)/C=C/O1)C)OC(C)=O)C)O)C)[C@@H](C)/C=C/C=C(C)\C(NC2=C3OC4=C(C=CC(OCCN(C)C)=C4)N=C3C5=C6C([C@]1(C)OC6=C(C)C(O)=C5C2=O)=O)=O
• Molecular Weight: 871.97
• References & Citations: [1]Thomas Nittoli, et al. Potent Rifampicin derivatives can clear MRSA infections at single low doses when concomitantly dosed with Vancomycin. J Antibiot (Tokyo). 2023.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported