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WS-917

CAT: 0804-HY-168528-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-168528-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WS-917 is a potent and orally active ABCB1 modulator. WS-917 enhances ABCB1 ATPase activity. WS-917 significantly enhances the antitumor effect of paclitaxel combined with anti-PD-1 antibody. WS-917 promotes CD8+ T-cell activation[1].
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ws-917.html
Purity
99.92
Smiles
O=C1C2=C(NC3=NC(SCC4=NC5=C(S4)C=CC=C5)=NN13)CCC2
Molecular Formula
C16H13N5OS2
Molecular Weight
355.44
References & Citations
[1]Wang S, et al. Cell-Based Screen Identifies a Highly Potent and Orally Available ABCB1 Modulator for Treatment of Multidrug Resistance. J Med Chem. 2024 Oct 19.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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